Introduction to Long-read Bioinformatics workshop, Jan 30 - Feb 1 Overview Whole genome sequencing (WGS) has been revolutionised by the development of long-read sequencing technologies in the last few years. Driven in no small part by Oxford Nanopore technologies (https://nanoporetech.com/) and Pacific Biosciences, HiFi (https://www.pacb.com/technology/hifi-sequencing/), we now have the ability to sequence long (mb+) single-molecule DNA fragments. Although these developments are expected to alleviate numerous computational challenges surrounding genome analysis they also bring some interesting bioinformatics challenges to which we have to adapt in order to get the most from this powerful technology. This exciting new course aims to introduce the principles and practice using long-read data analysis with focus on Oxford Nanopore data. We will present the cutting edge software and best practices tried and tested by our expert bioinformaticians at Edinburgh Genomics. Who this course is for Aside from a basic understanding of molecular biology, attendees must have a working knowledge of how to use the Linux BASH command line - our 1-day "Linux for bioinformatics" course is a suitable background. Instructor Urmi Trivedi - Bioinformatics Team Leader, Edinburgh Genomics Heleen De Weerd - Bioinformatician/Analyst, Edinburgh Genomics Workshop format The workshop consists of presentations and hands-on tutorials. Topics covered Introduction to long read sequencing technologies Long read data pre-processing (Nanopore + PacBio) Mapping to a reference genome (minimap2) Structural variant detection using long reads (NGMLR, sniffles, cuteSV, SURVIVOR, IGV) De novo genome assembly using long reads (flye, Redbean) Assessment of genome assembly (QUAST/BUSCO) Polishing of genome assembly (MarginPolish/HELEN) Related Links Edinburgh Genomics Jan 30 2023 10.00 - Feb 01 2023 15.00 Introduction to Long-read Bioinformatics workshop, Jan 30 - Feb 1 This exciting new course aims to introduce the principles and practice using long-read data analysis with focus on Oxford Nanopore data. We will present the cutting edge software and best practices tried and tested by our expert bioinformaticians at Edinburgh Genomics. Register here
Introduction to Long-read Bioinformatics workshop, Jan 30 - Feb 1 Overview Whole genome sequencing (WGS) has been revolutionised by the development of long-read sequencing technologies in the last few years. Driven in no small part by Oxford Nanopore technologies (https://nanoporetech.com/) and Pacific Biosciences, HiFi (https://www.pacb.com/technology/hifi-sequencing/), we now have the ability to sequence long (mb+) single-molecule DNA fragments. Although these developments are expected to alleviate numerous computational challenges surrounding genome analysis they also bring some interesting bioinformatics challenges to which we have to adapt in order to get the most from this powerful technology. This exciting new course aims to introduce the principles and practice using long-read data analysis with focus on Oxford Nanopore data. We will present the cutting edge software and best practices tried and tested by our expert bioinformaticians at Edinburgh Genomics. Who this course is for Aside from a basic understanding of molecular biology, attendees must have a working knowledge of how to use the Linux BASH command line - our 1-day "Linux for bioinformatics" course is a suitable background. Instructor Urmi Trivedi - Bioinformatics Team Leader, Edinburgh Genomics Heleen De Weerd - Bioinformatician/Analyst, Edinburgh Genomics Workshop format The workshop consists of presentations and hands-on tutorials. Topics covered Introduction to long read sequencing technologies Long read data pre-processing (Nanopore + PacBio) Mapping to a reference genome (minimap2) Structural variant detection using long reads (NGMLR, sniffles, cuteSV, SURVIVOR, IGV) De novo genome assembly using long reads (flye, Redbean) Assessment of genome assembly (QUAST/BUSCO) Polishing of genome assembly (MarginPolish/HELEN) Related Links Edinburgh Genomics Jan 30 2023 10.00 - Feb 01 2023 15.00 Introduction to Long-read Bioinformatics workshop, Jan 30 - Feb 1 This exciting new course aims to introduce the principles and practice using long-read data analysis with focus on Oxford Nanopore data. We will present the cutting edge software and best practices tried and tested by our expert bioinformaticians at Edinburgh Genomics. Register here
Jan 30 2023 10.00 - Feb 01 2023 15.00 Introduction to Long-read Bioinformatics workshop, Jan 30 - Feb 1 This exciting new course aims to introduce the principles and practice using long-read data analysis with focus on Oxford Nanopore data. We will present the cutting edge software and best practices tried and tested by our expert bioinformaticians at Edinburgh Genomics.
