We were very pleased to host our Next Generation of Genomics event on May 31 and June 1, 2022. The Next Generation of Genomics Symposium was organised to give young researchers in the field of genomics the opportunity to present their amazing research findings.More than 30 young researchers presented high quality science and covered a broad spectrum of genomics from across the University of Edinburgh.We were particularly pleased that Dr. Amanda Warr from the Roslin Institute, Dr. Alex Twyford from the Institute of Evolutionary Biology, Dr. Joshua Quick from the University of Birmingham, and Dr. Benjamin Werner from the CRUK Barts Centre were the keynote speakers. Document The Next Generation of Genomics Symposium programme (32.97 KB / DOCX) 2022 Prize winnersThe best presentations at the 1st Next Generation of Genomics symposium:- Eleni Papachristoforou, Single-cell transcriptomics defines pathogenic macrophages in murine liver fibrosis - Centre of Inflammation Research- Lucia Campos-Dominguez, Sequencing and assembly of a monster plant genome - Institute of Evolutionary Biology- Jon Bancic, Genomic and phenotypic characterization of finger millet - The Roslin Institute Image Closing remarks by the Director at the end of the SymposiumWhat a great day! It was absolutely fantastic to hear the breath and depth of expertise on display today, which definitely tells us that we have a bright future ahead of us in genomics at the University of Edinburgh.Prof Mick Watson, Director Genomics at EdinburghListen againIf you missed the event or want to listen to the presentations again, you can find the recordings below.PresentationsWelcome and Introduction Mick Watson, Director Genomics at EdinburghGenomic fruits from the green tree of life Alex Twyford, The institute of Evolutionary BiologyRevealing functional and genomic differences between two species of the megadiverse genus Begonia Katie Emelianova, The Royal Botanic Garden EdinburghSequencing and assembling a monster plant genome Lucia Campos-Dominguez, Institute of Evolutionary BiologyDe novo genome sequencing and assembly of an industrially-relevant microalga Martina Dajak, Institute of Quantitative Biology, Biochemistry and BiotechnologyGenomic and phenotypic characterization of finger millet Jon Bancic, The Roslin InstituteGenomic prediction into future crop growing environments Daniel Tolhurst, The Roslin InstituteBiofoundry DNA assembly validation using long reads Peter Vegh, Edinburgh Genome FoundryThe evolutionary dynamics of chromosomal and extra-chromosomal DNA in human cancers Benjamin Werner, CRUK Barts CentreImputed transcriptome risk scores reveal gene expression-based resemblance among human couples for height Vasilios Raptis, Institute of Genetics and CancerMarked regional glial heterogeneity in the human white matter of the central nervous system Luise Seeker, Centre for Regenerative MedicineAnalysis of genomic, mitochondrial and bacterial DNA using shotgun metagenomics sequencing of circulating blood cell-free DNA in Inflammatory Bowel Disease (IBD) Shaun Chuah, Centre for Inflammation ResearchElucidating long range connectivity of the entorhinal cortex through Multiplexed Analysis of Projections by Sequencing Sara Gómez Arnaiz, Centre for Discovery Brain SciencesFast and Efficient Genotype Compression for Genome-Wide Association Studies Mulya Agung, MRC University Unit for Human GeneticsTowards ultra-rapid microbial cf-DNA Nanopore Sequencing for detection of sepsis-causing pathogens Ana Martinez-Lopez, Heriot Watt University - UoE Infection MedicineSingle-cell transcriptomics defines pathogenic macrophages in murine liver fibrosis Eleni Papachristoforou, Centre of Inflammation ResearchHarnessing genome characterisation to uncover disease mechanisms Silvia Shen, Institute of Evolutionary Biology, Institute for Cancer and GeneticsA Nextflow pipeline for reproducible transcriptome-driven codon usage analysis Anima Sutradhar, IQB3 - Centre for Systems and Synthetic BiologySingle-cell sequencing techniques for metagenomics and antibiotic resistance prediction Joshua Quick, University of BirminghamIdentifying germline progenitors through single cell multiomics Sara Gonzalez Brito, Centre for Regenerative MedicineOTX2 modulates chromatin accessibility at somatic enhancers Elisa Barbieri, Institute for Stem Cell ResearchAssociations of major psychiatric disorders and cross-disorder polygenic risk scores with inflammatory blood markers Amelia Edmondson-Stait, Psychiatry DepartmentComparative population genomics of red squirrels in Scotland: understanding diversity in a key stronghold Melissa Marr, The Royal (Dick) School of Veterinary StudiesGenomic consequences of conservation management strategies in scimitar-horned oryx Emily Humble, The Royal (Dick) School of Veterinary StudiesEnvironmental genomics as a new tool to trace the origin of falsified antimicrobials Carla Perez Mon, The Royal (Dick) School of Veterinary StudiesPopulation genetics of an elusive marine predator, the Atlantic white-sided dolphin (Lagenorhynchus acutus), across the eastern North Atlantic Marc-Alexander Gose, The Royal (Dick) School of Veterinary StudiesGenome structural variation landscape in Nile Tilapia Zexin Jiao, The Roslin InstituteLong reads and small genomes: No assembly required? Amanda Warr, The Roslin InstituteDoGsTAils: Developing nanopore-based diagnostic approaches for the effective antimicrobial stewardship of canine infections Natalie Ring, The Roslin InstituteThird-generation sequencing to create a complete genome of Trypanosoma brucei Xin Lan, Zhejiang University-University of Edinburgh Institute (ZJE)Characterising a neo-sex chromosome in a fly with single-sex broods Robert Baird, Institute of Evolutionary BiologyUnderstanding the resilience of wild birds to climate change Zhou Wu, The Roslin instituteInvestigating the genetic architecture of complex traits in Soay sheep Caelinn James, Institute of Evolutionary BiologyBuilding genomic resources for dairy development in Rwanda Oluyinka Opoola, Centre for Tropical Livestock Genetics and Health (CTLGH)Exploring the microbiota of livestock using metagenomics Laura Glendinning, The Roslin InstituteInvestigating the impact of database choice on the accuracy of metagenomic read classification for the rumen microbiome Rebecca Smith, The Roslin Institute Publication date 03 Nov, 2022
